In the ten years since the initial sequencing of the human genome, the emergence of low-cost DNA sequencing technologies has enabled researchers to pursue projects never before possible. Genomics has rapidly found applications in fields ranging from microbial ecology to vaccine development to biodefense. Studies utilizing genomics are often highly interdisciplinary: each project requires a team of scientists with different specialties depending on the goals of the study. As the cost of sequencing continues to drop and throughput continues to grow, a major challenge is how to best handle so much data. The purpose of my work is to help researchers analyze massive amounts of data produced by the latest sequencing technologies in order to address their hypotheses.
Despite the increasing popularity of genomics, there remains a disconnect between many computational groups and experimental biology labs. Contributing factors to this issue include the current organization of academic departments in our universities and differing priorities among PIs. To explore how we can better improve this essential connection, I'm teaming up with strong experimental labs around the country in hopes of finding new ways to answer their questions. If you're interested in collaborating, feel free to contact me.
12-2-2011: Characterizing the sea squirt microbiome - Proc Natl Acad Sci
10-20-2011: Costs of doing genomics in the cloud - PLoS One
9-15-2011: The CloVR paper is out! - BMC Bioinformatics
5-2-2011: Bacterial community diversity on the tomato surface - BMC Micro
Twitter: @jamesdnawhite
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